Six previous buildings occupied the place of the Catedral Metropolitana de Buenos Aires (Buenos Aires Metropolitan Cathedral). The current cathedral was built from 1752 to 1852 with its decoration completed in 1911. The cathedral's neoclassical style has more in common with a Greek temple than with a traditional Catholic church.
The facade's twelve columns represent the twelve apostles. Inside, there are five aisles and the dome reaches a height of more than 40 metres.
The cathedral is built on the square dedicated to General San Martín, the liberator of Argentina and houses his tomb.